2-ETHYL-2 H-PYRAZOLE-3-CARBOXYLIC ACID HYDRAZIDE - Names and Identifiers
2-ETHYL-2 H-PYRAZOLE-3-CARBOXYLIC ACID HYDRAZIDE - Physico-chemical Properties
Molecular Formula | C6H10N4O
|
Molar Mass | 154.17 |
Density | 1.35±0.1 g/cm3(Predicted) |
pKa | 12.14±0.10(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD03423248 |
2-ETHYL-2 H-PYRAZOLE-3-CARBOXYLIC ACID HYDRAZIDE - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
2-ETHYL-2 H-PYRAZOLE-3-CARBOXYLIC ACID HYDRAZIDE - Introduction
1-Ethyl-1H-pyrazole-5-carbohydrazide is an organic compound with the chemical formula C7H10N4O. It is a white crystalline solid, stable at room temperature. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 182.18g/mol
-melting point: 120-123 ℃
-Solubility: Soluble in alcohol and ketone solvents, insoluble in water
Use:
1-Ethyl-1H-pyrazole-5-carbohydrazide has many uses in chemical research and synthesis, such:
-as an intermediate in organic synthesis reactions
-Used as raw materials for pesticides, pharmaceuticals and dyes
-Used as a ligand in metal coordination chemistry
Preparation Method:
The method for preparing 1-ethyl-1H-pyrazole-5-carbohydrazide is mainly carried out by the following steps:
1. First, ethyl pyruvate is reacted with hydrazine to obtain ethyl-2-aminopyruvate.
2. reacting ethyl -2-aminopyruvate with an acid catalyst to generate 1-ethyl -1H-pyrazol-5-one.
3. Finally, 1-ethyl-1H-pyrazol-5-one is reacted with hydrazine to obtain 1-ethyl-1H-pyrazole-5-carbohydrazide.
Safety Information:
1-Ethyl-1H-pyrazole-5-carbohydrazide has not been reported to cause serious harm to human health. However, when handling and using the compound, protective measures should be taken to avoid contact with skin, eyes and respiratory tract. At the same time, it should be stored in a closed container, away from heat and fire sources. It is best to wear personal protective equipment such as gloves, goggles and protective clothing before use. Pay attention to ventilation during handling and follow relevant safety operation guidelines. In the event of an accident, a doctor should be called immediately and detailed chemical information should be provided. To ensure safety, please use the compound in strict accordance with relevant regulations and guidelines.
Last Update:2024-04-09 21:32:51